François Weigel studied conducting and composition at the Musikhochschule of Cologne, the Paris Conservatoire, and advanced pianistic studies with Alexis Weissenberg. As a concert pianist, he has played with many leading orchestras like the Hamburg Philharmonic (with Ingo Metzmacher), the Warsaw Philharmonic Orchestra (Antoni Wit) the Orchestre de la Suisse Romande (Pinchas Steinberg), the Orchestre Philharmonique de Radio-France (Marek Janowsky), the Orchestre National de France (Jacques Mercier), the Orchestre National de Lille (Jean-Claude Casadesus).

He gives many concerts throughout Europe and has performed in the Berliner Philharmonie, Vienna, Bruxelles, Oslo, Naples, Riga, Paris, the international festival of Evian, La Roque d’Antheron, Verone, Stresa, Dallas, Buenos Aires.

His recitals of the complete Chopin Studies, the Liszt Rhapsodies, or his own opera transcriptions, in Paris Salle Gaveau and Radio-France are widely acclaimed for the originality of his interpretation.